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Scalco, Renata S.; Lucia, Alejandro; Santalla, Alfredo; Martinuzzi, Andrea; Vavla, Marinela; Reni, Gianluigi; Toscano, Antonio; Musumeci, Olimpia; Voermans, Nicol C.; Kouwenberg, Carlyn V.; Laforêt, Pascal; San-Millán, Beatriz; Vieitez, Irene; Siciliano, Gabriele; Kühnle, Enrico (2020-11-24). "Data from the European registry for patients with McArdle illness and other muscle glycogenoses (EUROMAC)". Orphanet Journal of Rare Diseases. Schneider, Joseph; Burmeister, Lynn A.; Rudser, Kyle; Whitley, Chester B.; Jarnes Utz, Jeanine (September 2016). "Hypothyroidism in late-onset Pompe illness".<br><br>However, throughout current many years, research has clearly shown that lengthy-term stress might be related to low cortisol and suppressed HPA axis activation, and this state of low cortisol is associated with CFS, PTSD and burnout. Whether or not the stress causes hypocortisolism relies on the nature of the menace, the time since onset, and the particular person's response to the situation. 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